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Uric Acid Crystals in Urine

Uric Acid Crystals Since about 75% of uric acid is excreted from the body via the kidneys, uric acid crystals are often found in morning urine during microscopic examination. These crystals appear when the urine pH is acidic (below 6). They do not hold particular clinical significance unless there is also an elevated level of...

Macroprolactin

What is macroprolactin and why is it measured? Macroprolactin (MCPRL) is a biological protein marker found in the blood of individuals showing symptoms of hyperprolactinemia, or elevated prolactin levels. It is a biologically inactive complex of prolactin monomers and immunoglobulin G (IgG). Prolactin in this complex is detected by most prolactin immunoassays, and thus contributes...

Pituitary Gland

What is the pituitary gland? The pituitary gland (Hypophysis) is a gland located at the base of the skull in a bony cavity called the sella turcica (Turkish saddle). The pituitary itself is small (1 cm) and is divided into two parts or lobes: Anterior lobe (adenohypophysis) Posterior lobe (neurohypophysis) These lobes have different origins;...

D-dimer as a Marker of Thrombosis

When it comes to thrombosis, one of the diagnostic methods is measuring the level of D-dimer in the blood, as one of the many markers used in medicine. However, before discussing the role of D-dimer in diagnosing thrombosis in more detail, we should first explain what D-dimer is and how a thrombus (blood clot) forms....

The Importance of Laboratory Tests in Disease Prevention

One of the most important steps in maintaining health is prevention. Maintaining a healthy lifestyle, regular check-ups, and routine medical exams are just some of the key elements in preventing diseases. What are routine medical exams? Routine medical exams include a series of laboratory tests conducted to assess the functioning of our body. The importance...

Symptoms of Iron Deficiency – How to Recognize Anemia

What is anemia? Anemia is a medical term that describes a deficiency of healthy red blood cells (erythrocytes) in the body. It can be caused by genetic predisposition or by iron deficiency due to inadequate nutrition or improper iron absorption in the body. Symptoms of anemia The symptoms of anemia can be mild and almost...

Inhibin B in Men and Women

Inhibin B as a Biomarker of Spermatogenesis in Men and Ovarian Reserve in Women What is Inhibin B? Inhibin B is a glycoprotein produced in the testes (by Sertoli cells) in men and in the ovaries (by granulosa cells) in women. It consists of two subunits connected by a disulfide bond, an alpha subunit and...

What is Bordetella pertussis or Whooping Cough?

What is Whooping Cough? Commonly known as whooping cough or pertussis, this is an acute, highly contagious disease caused by the bacterium Bordetella pertussis (B. pertussis). Whooping cough was first mentioned in literature between 1414 and 1540, with the first description of an epidemic dating back to 1578. The causative agent, Bordetella pertussis, was isolated...